Table 5.
Major features of the 25 infants with Food protein-induced proctitis/proctocolitis.
| Patient (sex) | Age month | Diet | dg. parents | a-pANCA IgG IIF |
a-pANCA IgA IIF |
ANA IgG IIF |
ANCA profile ELISA |
ASCA IIF |
a-EMA IgA |
a-EMA IgG |
a-tTg IgA |
a-tTg IgG |
Prick tests cow's milk egg |
Phadiatop MJ/mL |
FX5 MJ/mL |
Calprotectin ng/mL <3000 ng/mL |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 (M) | 6 | Milk hydrolyzate | — | Positive | Neg. | Neg. | Neg. | Neg. | — | — | 1 | 1 | Negative | — | <0.35 | — |
| 2 (F) | 2 | Breastfeeding | Mother IA | Highly positive | Positive | Neg. | Neg. | Neg. | Neg. | Neg. | 0.5 | 1 | Negative | — | <0.35 | 390 |
| 3 (F) | 5 | Milk hydrolyzate | Mother IA | Highly positive | Neg. | Neg. | Neg. | Neg. | — | — | — | — | Negative | <0.35 | <0.35 | 339 |
| 4 (M) | 2 | Breastfeeding | Mother IA | Highly positive | Neg. | Neg. |
Positive
ELAST. |
Neg. | — | — | — | — | Negative | <0.35 | <0.35 | 511 |
| 5 (F) | 7 | Milk hydrolyzate | — | Highly positive | Neg. | Positive (granular) | Neg. | Neg. | — | — | — | — | Negative | — | — | 4286 |
| 6 (F) | 24 | Egg-free diet | Mother IA | Positive | Neg. | Neg. | Neg. | Neg. | Neg. | Neg. | 1.2 | 1 | Negative | 2.22 | <0.35 | 4451 |
| 7 (F) | 1 | Breastfeeding | — | Positive | Neg. | Neg. | Weakly positive PR3 | Neg. | Neg. | Neg. | 0.5 | 0.9 | Negative | <0.35 | <0.35 | 677 |
| 8 (M) | 1 | Breastfeeding | Father IA | Weakly positive | Neg. | Neg. | Neg. | Neg. | — | — | — | — | Negative | <0.35 | 385 | |
| 9 (M) | 24 | — | Mother IA | Positive | Neg. | Neg. | Neg. | Neg. | — | — | — | — | Negative | <0.35 | <0.35 | — |
| 10 (M) | 2 | Breastfeeding | — | Positive | Neg. | Neg. | Neg. | Neg. | — | — | — | — | Negative | — | — | — |
| 11 (M) | 3 | Breastfeeding | Mother, father IA | Positive | Neg. | Neg. | Neg. | Neg. | — | — | — | — | Negative | — | <0.35 | 83 |
| 12 (F) | 24 | Mother IA, FA | Weakly positive | Neg. | Neg. | Neg. | Neg. | Neg. | Neg. | 1.1 | 1 | Negative | <0.35 | <0.35 | 620 | |
| 13 (F) | 7 | Milk hydrolyzate | Mother IA, FA | Positive | Neg. | Neg. | Neg. | Neg. | — | — | — | — | Negative | <0.35 | <0.35 | 376 |
| 14 (M) | 23 | — | — | Positive | Highly positive | Neg. |
Weakly positive
PR3 |
Neg. | Neg. | Neg. | 2.69 | 1.1 | Negative | — | <0.35 | 641 |
| 15 (F) | 24 | — | Mother IA | Positive | Positive | Neg. |
Positive
ELAST. |
Neg. | Neg. | Neg. | 1 | 1.2 | Negative | <0.35 | <0.35 | 1014 |
| 16 (M) | 4 | Milk hydrolyzate | — | Positive | Neg. | Neg. | Neg. | Neg. | — | — | 1.1 | 1.1 | Negative | <0.35 | <0.35 | 510 |
| 17 (F) | 18 | Egg-free diet | Father IA | Positive | Neg. | Neg. | Neg. | Neg. | — | — | 1.1 | 1.2 | Negative | — | — | 548 |
| 18 (M) | 15 | — | Father IA | Neg. | Positive | Neg. | Neg. | Neg. | Neg. | Neg. | 1.1 | 1 | Negative | <0.35 | <0.35 | 1270 |
| 19 (F) | 18 | — | Mother celiakie | Highly positive | Neg. | Neg. | Neg. | Neg. | Neg. | Neg. | 1 | 1 | Negative | <0.35 | <0.35 | 1784 |
| 20 (F) | 6 | Milk hydrolyzate | — | Highly positive | Highly positive | Neg. | Neg. | Neg. | Neg. | Neg. | 1 | 1.1 | Negative | — | — | 821 |
| 21 (F) | 4 | Milk hydrolyzate | Father IA | Positive | Neg. | Neg. | Neg. | Neg. | Neg. | Neg. | 0.5 | 1.9 | Negative | <0.35 | 0.97 | 340 |
| 22 (M) | 6 | Milk hydrolyzate | Father ulcerative colitis | Positive | Neg. | Neg. | Neg. | Neg. | — | — | — | — | Negative | — | >100 | 443 |
| 23 (M) | 15 | Egg-free diet | — | Positive | Neg. | Neg. | Neg. | Neg. | — | — | — | — | Negative | — | — | 952 |
| 24 (F) | 1 | Breastfeeding | — | Highly positive | Neg. | Neg. | Neg. | Neg. | — | — | — | — | Negative | <0.35 | — | 454 |
| 25 (M) | 1 | Breastfeeding | Father IA | Weakly positive | Neg. | Neg. | Neg. | Neg. | — | — | — | — | Negative | <0.35 | <0.35 | 980 |
IA: inhalation allergy.
FA: food allergy.