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. Author manuscript; available in PMC: 2015 Oct 5.
Published in final edited form as: Neurobehav HIV Med. 2011;3:79–86. doi: 10.2147/NBHIV.S22553

Table 2.

Sensitivity and specificity for standard and alternate cutoff scores when compared with consensus diagnosis (n = 21)

Measure AUC Standard cutoff Alternate cutoff Sensitivity Specificity
MMSE 0.40 <24 N/A 8% 88%
28 25% 59%
29 50% 60%
HDS 0.63 ≤10 N/A 67% 50%
11 70% 25%
12 75% 19%
NEUROPSI* 0.59 Varied N/A 75% 38%
90 75% 61%

Notes:

*

NEUROPSI ordinal score (normal, mild, moderate, severe impairment). Cutoff scores are based on demographic strata. Sensitivity and specificity for standard cutoff scores based on collapsing all impaired strata. Alternative cutoff scores based on unstratified raw score for entire sample.

Abbreviations: AUC, area under the curve; HDS, HIV Dementia Scale; MMSE, Mini-Mental State Examination; N/A, not applicable.