Table 2.
Measure | AUC | Standard cutoff | Alternate cutoff | Sensitivity | Specificity |
---|---|---|---|---|---|
MMSE | 0.40 | <24 | N/A | 8% | 88% |
28 | 25% | 59% | |||
29 | 50% | 60% | |||
HDS | 0.63 | ≤10 | N/A | 67% | 50% |
11 | 70% | 25% | |||
12 | 75% | 19% | |||
NEUROPSI* | 0.59 | Varied | N/A | 75% | 38% |
90 | 75% | 61% |
Notes:
NEUROPSI ordinal score (normal, mild, moderate, severe impairment). Cutoff scores are based on demographic strata. Sensitivity and specificity for standard cutoff scores based on collapsing all impaired strata. Alternative cutoff scores based on unstratified raw score for entire sample.
Abbreviations: AUC, area under the curve; HDS, HIV Dementia Scale; MMSE, Mini-Mental State Examination; N/A, not applicable.