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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Health Phys. 2015 Nov;109(5):414–426. doi: 10.1097/HP.0000000000000348

Table 1. Neutrophil-related parameters for rhesus macaques following x-irradiation.

Animals were exposed to 250 kVp x-radiation at 6.00 Gy total body irradiation. The mean, standard error (SEM), median and range for neutrophil-related parameters are reported. The day of the occurrence of neutropenia [absolute neutrophil count (ANC) < 500 cells μL-1 or < 100 cells μL-1, respectively] is shown. The duration of neutropenia was estimated as the number of days that a subject had an observed or extrapolated ANC < 500 cells μL-1 or < 100 cells μL-1. Any single observed ANC that was ≥ 500 cells μL-1 and was immediately preceded and followed by ANC < 500 cells μL-1 was counted as a day of neutropenia. The time to recovery was determined as the number of days from study day 1 until the first 2 consecutive days observed or extrapolated to an ANC ≥ 500 cells μL-1 or 1,000 cells μL-1 after the nadir.

First day (d) of Neutropenia (cells μL-1) Duration (d) of Neutropenia (cells μL-1) Day of Recovery a ANC (cells μL-1) (day) Nadir a (cells μL-1)
ANC<500a ANC<100b ANC<500a ANC<100b ANC≥500 ANC≥1,000 ANC
Mean ± SEM 5.5 ± 0.2 10.5 ± 0.8 15.1 ± 0.6 6.3 ± 1.2 20.9 ± 0.6 22.6 ± 0.7 51 ± 17
Median 6.0 11.0 15.0 6.5 21.5 23.0 31
Range d4 - 7 d6 - 18 d12 - 20 d0 - 15 d18 - 25 d19 - 28 0 - 210
a

n = 14

b

n = 12