Table 2.

Reaction of RPP 19 with pyrazole and with 2-chloroimidazole nucleophiles in the presence and absence of magnesium iodide

Entry	Nucleophiles	Additive	Product	Yield, %
1*	Pyrazole	No additive	20	—
2*	Pyrazole	MgI2	20	30
3†	2-Chloroimidazole	No additive	21	Trace
4†	2-Chloroimidazole	MgI2	21	48

^*Compound 19 (0.1 M), MgI₂ (0.4 M), pyrazole (0.2 M), DMF (solvent).

^†Compound 19 (0.1 M), MgI₂ (0.4 M), 2-chloro imidazole (0.8 M), DMF (solvent).