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. 2015 Oct 5;12:23. doi: 10.1186/s12987-015-0019-5

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© Bedussi et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Penetration of TR-3 in the choroid plexus after striatum injection. Horizontal section −3 mm from the bregma. a–d Overview of the lateral ventricle. F-500 accumulated towards the ependymal layer (a) while TR-3 appeared to cross the ependymal more easily (b). Cell nuclei stained with DAPI (c). A merged picture is shown in panel d. e–g Detail of the choroid plexus. F-500 remains confined to the surface of the choroid plexus (e) while TR-3 clearly penetrated the choroid plexus (f). Cell nuclei stained with DAPI (g). Merged picture (h). Scale bar 100 µm