Table 3.
Allele distributions of SNPs in MUC17 gene vs. CA-125 level
| Polymorphism | CA125 ≥ 35 c | CA125 < 35 | P-value a | Corrected P-value b | OR | 95 % CI |
|---|---|---|---|---|---|---|
| MAF | MAF | |||||
| rs4729645 | 15.1 | 13.6 | 0.76 | 3.80 | 1.12 | 0.61-2.13 |
| rs10953316 | 13.0 | 12.5 | 0.91 | 4.55 | 1.03 | 0.42-2.51 |
| rs74974199 | 14.4 | 5.7 | 0.045* | 0.225 | 2.75 | 0.99-7.61 |
| rs4729655 | 64.4 | 46.6 | 0.0076* | 0.038* | 2.08 | 1.20-3.57 |
| rs4729656 | 28.8 | 44.3 | 0.015* | 0.075 | 0.49 | 0.28-0.87 |
*Indicates statistical significance
MAF: minor allele frequency
aP-values were calculated using χ2 test
bP-values were corrected by Bonferroni correction
cCA125 level: KU/L