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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Semin Oncol. 2015 Jul 10;42(5):748–763. doi: 10.1053/j.seminoncol.2015.07.006

Table 4.

Ancillary Studies in Large Prostate and Breast Cancer Prevention Trials

Study Study Name PI/Organization Outcomes Evaluated Funding Agency
SELECT Prevention of Alzheimer's Disease with Vitamin E and Selenium (PREADVISE) NCT00040378 Frederick Schmitt, Ph.D., Richard Kryscio, Ph.D., University of Kentucky To determine if supplements studied can help prevent memory loss and dementia. National Institute on Aging
SELECT Eye Endpoints Study (SEE) NCT00784225 William Christen, Sc.D. Harvard Medical School Long-term daily supplementation with selenium and/or vitamin E is unlikely to have a large beneficial effect on age-related cataract.
Christin, et al, JAMA Opthalmol, 2014.
National Eye Institute
Respiratory Ancillary Study NCT00782678 Patricia A. Cassano, Ph.D. Weill Medical College of Cornell University To understand whether supplements being studied have an impact upon loss of lung function from aging. National Heart, Lung and Blood Institute
Colon Polyps Sub Study NCT00706121 M. Peter Lance, M.D. Arizona Cancer Center To see if the supplements affect the growth of colon polyps National Cancer Institute
STAR Co-STAR (Cognition in the Study of Tamoxifen and Raloxifene) NCT00687102 Sally Shumaker, Ph.D. Wake Forest School of Medicine Compare the effects of tamoxifen and raloxifene on cognitive functions, such as thinking and memory National Institute on Aging