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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Health Phys. 2015 Nov;109(5):391–398. doi: 10.1097/HP.0000000000000354

Table 1.

Administration schedule, route, radiation dose, expected and actual LDXX/30, and number of mice in each Admn group.

Group Study Number Days of vehicle administration Route Radiation dose (Gy) Expected LDXX/30 Actual LDXX/30 Number of mice
Admn 1 1 none none 8.53 LD50/30 LD52/30 15

2 none none 8.53 LD50/30 LD68/30 44

3 none none 8.53 LD50/30 LD40/30 38

4 none none 8.53 LD50/30 LD67/30 103

5 none none 8.53 LD50/30 LD39/30 74

Admn 2 6 1 SQ 8.53 LD50/30 LD35/30 20
8.72 LD70/30 LD55/30 20

7 1, 3, & 5 SQ 8.53 LD50/30 LD55/30 20
8.72 LD70/30 LD75/30 20

8 1 & 5 IM 8.53 LD50/30 LD47/30 17
8.72 LD70/30 LD67/30 18
9.04 LD90/30 LD78/30 18

9 1 SQ 8.53 LD50/30 LD40/30 20
8.72 LD70/30 LD90/30 20

10 1 SQ 8.53 LD50/30 LD95/30 20
8.72 LD70/30 LD55/30 20

11 2 SQ 8.53 LD50/30 LD70/30 20
8.72 LD70/30 LD90/30 20

12 1 & 2 SQ 8.53 LD50/30 LD59/30 17
8.72 LD70/30 LD71/30 17
9.04 LD90/30 LD88/30 17

13 1 SQ 8.72 LD70/30 LD65/30 20
9.27 LD96/30 LD95/30 20

14 1 SQ 9.27 LD96/30 LD90/30 20

15 3 SQ 8.53 LD50/30 LD45/30 20
8.72 LD70/30 LD75/30 20

16 1, 2, & 3 SQ 8.53 LD50/30 LD40/30 20
8.72 LD70/30 LD60/30 20

Admn 3 17 1, 3, 5, 7, 9, & 11 gavage 8.53 LD50/30 LD63/30 40
8.72 LD70/30 LD90/30 39

18 Daily on days 1 thru 29 SQ 8.53 LD50/30 LD95/30 20
8.72 LD70/30 LD100/30 20

19 1, 3, 5, 7, 9, & 11 gavage 8.34 LD30/30 LD30/30 20
8.53 LD50/30 LD65/30 20

20 1, 3, 5, 7, 9, 11, 13, 15, & 17 gavage 8.34 LD30/30 LD35/30 20
8.53 LD50/30 LD70/30 20