Table 4.

Independent prognostic factors from multivariate analysis for OS

Variable	HR	95% CI	P value
Age (≥48 years/<48 years)	1.24	0.99–1.57	0.059
UICC N stage (N1–3/N0)	1.84	1.06–3.19	0.031
Number of metastatic lesions (multiple/single)	1.60	117–2.20	0.005
Liver involvement (yes/no)	1.56	1.23–1.96	<0.001
Cycles of chemotherapy (>4/≤4)	0.63	0.50–0.79	<0.001
Radiotherapy to primary tumor (yes/no)	0.59	0.47–0.75	<0.001

UICC International Union Against Cancer, HR hazard ratio, CI confident interval.