Table 2.
Outcomes and efficacy of mobilization in 39 patients with high-risk non-Hodgkin’s lymphoma
| Parameter | All patients (n = 39) | R-CHOP (n = 14) | CHOP (n = 25) | P value |
|---|---|---|---|---|
| Time from mobilization chemotherapy to rhG-CSF support (days)a | 9 (6–15) | 12.5 (9–15) | 12 (6–15) | 0.082 |
| Duration of rhG-CSF support (days)a | 5 (3–10) | 5 (3–9) | 5 (4–10) | 0.343 |
| Time from mobilization chemotherapy to apheresis (days)a | 16 (12–20) | 16.5 (15–18) | 16 (12–20) | 0.032 |
| Percentage of CD34+ cells in peripheral blood on the first day of apheresis (%)a | 2.43 (0.36–7.50) | 1.35 (0.36–3.41) | 3.14 (1.14–7.50) | 0.002 |
| Peripheral blood WBC count on the first day of apheresis (×109/L)a | 14.30 (3.55–43.20) | 10.35 (3.55–43.20) | 17.15 (5.56–41.60) | 0.031 |
| Number of apheresis proceduresa | 1 (1–3) | 1 (1–2) | 1 (1–3) | 0.593 |
| CD34+ cells collected on day 1 (×106 cells/kg body weight)a | 5.79 (0.40–18.50) | 4.83 (1.03–8.11) | 7.07 (0.40–18.50) | 0.016 |
| CD34+ cells collected in total (×106 cells/kg body weight)a | 7.01 (1.49–28.39) | 5.01 (1.49–13.40) | 8.25 (1.61–28.39) | 0.005 |
| CD34+ cells collected per apheresis (×106 cells/kg body weight)a | 5.97 (0.75–18.50) | 4.83 (0.75–8.11) | 7.31 (0.81–18.50) | 0.014 |
| Optimal mobilization of CD34+ cell collection [cases (%)] | 27 (69.2) | 7 (50.0) | 20 (80.0) | 0.075 |
| Successful mobilization of CD34+ cells [cases (%)] | 37 (94.5) | 13 (92.9) | 24 (96.0) | 1.000 |
rhG-CSF recombinant human granulocyte colony-stimulating factor, WBC white blood cell. Other abbreviations as in Table 1
aThe values are presented as median followed by range in parentheses; other values are presented as the number of patients followed by percentages in parentheses