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Domain distribution of cancer-related MxA single-point mutations
| MxA segment | Mutation(s) in cancers |
|---|---|
| GTPase domain (G domain) | L95P, P96S, S134L, P218S, V263M, R310S, K326N |
| Bundle-signaling-element domain (BSE) | L643V, R649W, T651M, R654Q, R655C |
| Stalk | G392V, V449G, N491K, R522C, L619I |
| Hinge 1 | E632K |
| L4 | G540D, Y538C, S572Y |
| N′-loop | T27S |
