Table 1.
Comparison of the clinical parameters between the two groups of patients with hepatocellular carcinoma (HCC)
| Matched variable | Combination group (n = 137) | Surgery group (n = 148) | P |
|---|---|---|---|
| Age (years) | 0.093 | ||
| Median | 51 | 54 | |
| Range | 23–74 | 23–75 | |
| Sexa | 0.183 | ||
| Male | 129 | 133 | |
| Female | 8 | 15 | |
| Hypersplenisma | 0.281 | ||
| Yes | 74 | 70 | |
| No | 63 | 78 | |
| Child-Pugh classa | 0.193 | ||
| A | 124 | 140 | |
| B | 13 | 8 | |
| Cirrhosisa | 0.432 | ||
| Yes | 118 | 132 | |
| No | 19 | 16 | |
| Diabetes mellitusa | 0.296 | ||
| No | 118 | 134 | |
| Yes | 19 | 14 | |
| Tumor numbera | 0.582 | ||
| 1 | 59 | 69 | |
| 2 | 43 | 50 | |
| 3 | 28 | 21 | |
| 4 | 7 | 8 | |
| Tumor sizea | 0.992 | ||
| ≤3 cm | 61 | 68 | |
| >3 cm and ≤5 cm | 47 | 49 | |
| >5 cm and ≤7 cm | 23 | 24 | |
| >7 cm and ≤10 cm | 6 | 7 | |
| Alpha fetoproteina | 0.292 | ||
| ≥400 ng/mL | 34 | 45 | |
| <400 ng/mL | 103 | 103 | |
| Size of all nodules in diameter (cm) | 0.364 | ||
| Median | 3.8 | 4.0 | |
| Mean ± standard deviation | 37.0 ± 17.5 | 38.9 ± 18.1 | |
| Albumin (g/L) | 40.8 ± 4.3 | 41.6 ± 4.2 | 0.133 |
| Prothrombin time (s) | 12.6 ± 2.0 | 13.0 ± 2.1 | 0.075 |
| Platelet count (×109/L) | 128.2 ± 64.8 | 145.1 ± 60.0 | 0.022 |
| Hemoglobin (g/L) | 135.9 ± 16.2 | 138.7 ± 16.8 | 0.156 |
| CA19-9 (U/mL) | 140.4 ± 852.2 | 79.8 ± 531.0 | 0.469 |
aThe values are presented as number of patients. Tumor size, the largest lesion in diameter.