Table 6.
Stratified Cox regression analysis of CRP-SAA, Total SAA, and CRP for 464 lung cancer patients
| Variable | Univariate model | Multivariate modela | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P | HR | 95% CI | P | |
| Stages I–II | ||||||
| CRP-SAA | ||||||
| Low level | 1.000 | 1.000 | ||||
| High level | 2.583 | 1.873–3.560 | <0.001 | 1.677 | 1.188–2.368 | 0.003 |
| Total SAA | ||||||
| Low level | 1.000 | 1.000 | ||||
| High level | 1.581 | 1.164–2.150 | 0.003 | 1.180 | 0.859–1.620 | 0.307 |
| CRP | ||||||
| Low level | 1.000 | 1.000 | ||||
| High level | 2.113 | 1.563–2.857 | <0.001 | 1.429 | 1.036–1.971 | 0.063 |
| Stages III–IV | ||||||
| CRP-SAA | ||||||
| Low level | 1.000 | 1.000 | ||||
| High level | 1.899 | 1.483–2.431 | <0.001 | 1.594 | 1.237–2.052 | <0.001 |
| Total SAA | ||||||
| Low level | 1.000 | 1.000 | ||||
| High level | 1.879 | 1.485–2.377 | <0.001 | 1.359 | 1.065–1.735 | 0.014 |
| CRP | ||||||
| Low level | 1.000 | 1.000 | ||||
| High level | 1.970 | 1.554–2.499 | <0.001 | 1.507 | 1.178–1.929 | 0.001 |
aEach serum marker was analyzed separately in the model, adjusting for age, sex, smoking status, clinical stage, and treatment. Abbreviations as in previous tables.