Table 6.

Genetic mutations and polymorphisms: results for autopsied cases

Genetic polymorphism or mutation	No. screened	No. positive (%)
Apolipoprotein E –ε4	1302	524 (40)
LRRK2 – G2019S polymorphism screened	237	3 (1.3)
Glucocerebrosidase (GBA) – all exons screened	247	18 (7.3)
Tau (MAPT) – screen of exons 1 and 9–13	45	3 (1.3)
Presenilin 1 – mutation screen	7	4 (57)
Progranulin (GRN) – screen of exons 1–13	31	4 (12.9)
C9orf72 – expansion screen	21	5 (24)
TDP43 (TARDBP)	1	0
Valosin-containing protein (VCP)	1	0
Charged multivesicular body protein 2B (CHMP2B)	1	0