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. Author manuscript; available in PMC: 2016 Aug 21.
Published in final edited form as: ACS Chem Biol. 2015 Jun 3;10(8):1916–1924. doi: 10.1021/acschembio.5b00367

Table 2.

IC50 Values for wt-p97 and Related ATPasesa

compound p97 GroEL ClpX NSF
1 44.0 ± 0.21 >200 >200 >200
2 21.6 ± 2.49 >200 9.47 ± 1.24 >200
3 78.1 ± 17.1 >200 >200 >200
4 19.0 ± 4.06 >200 >200 >200
5 >200 >200 >200 >200
6 21.9 ± 2.38 >200 >200 >200
7 48.3 ± 6.34 >200 >200 >200
8 40.9 ± 14.8 >200 >200 >200
9 17.7 ± 4.45 >200 >200 >200
10 >200 >200 >200 >200
11 32.2 ± 20.2 >200 >200 >200
12 >200 >200 >200 >200
13 >200 >200 >200 >200
14 >200 >200 >200 >200
15 >200 >200 35.5 ± 6.18 >200
16 >200 >200 >200 >200
17 53.7 ± 4.22 >200 >200 >200
18 >200 >200 21.8 ± 11.2 >200
19 21.9 ± 2.14 >200 >200 >200
a

IC50 values are given in μM inhibition of ATPase activity using the procedure provided in the Supporting Information.