Table 2. Clinical characteristics of hospitalized case-patients with confirmed severe fever with thrombocytopenia syndrome, by outcome, South Korea, 2013*.
| Characteristics | No. (%) case-patients |
p value† | ||
|---|---|---|---|---|
| Total, n = 35 | Died, n = 16 | Recovered, n = 19 | ||
| Fever/chills |
35 (100) |
16 (100) |
19 (100) |
1.000 |
| Fever, n = 32 | ||||
| ≤39.0°C | 25 (78) | 9 (64) | 16 (89) | 0.195 |
| >39.0°C |
7 (22) |
5 (36) |
2 (11) |
NA |
| Fatigue | 26 (74) | 11 (69) | 15 (79) | 0.700 |
| Myalgia | 19 (54) | 9 (56) | 10 (53) | 1.000 |
| Headache | 12 (34) | 4 (25) | 8 (42) | 0.476 |
| Cough | 7 (20) | 3 (19) | 4 (21) | 1.000 |
| Sputum |
9 (26) |
3 (19) |
6 (32) |
0.460 |
| Lymphadenopathy on physical examination | 5 (14) | 1 (6) | 4 (21) | 0.347 |
| Lymph node enlargement found by CT, n = 32 |
20 (63) |
7 (54) |
13 (68) |
0.473 |
| Gastrointestinal symptoms | ||||
| Overall | 33 (94) | 15 (94) | 18 (95) | 1.000 |
| Anorexia | 21 (60) | 8 (50) | 13 (68) | 0.317 |
| Nausea | 16 (46) | 5 (31) | 11 (58) | 0.176 |
| Abdominal pain | 9 (26) | 6 (38) | 3 (16) | 0.245 |
| Diarrhea | 22 (63) | 12 (75) | 10 (53) | 0.293 |
| Vomiting | 15 (43) | 6 (38) | 9 (47) | 0.734 |
| Diarrhea/vomiting |
26 (74) |
13 (81) |
13 (68) |
0.460 |
| Neurologic symptoms | ||||
| Overall | 27 (77) | 15 (94) | 12 (63) | 0.047 |
| Within 7 d after disease onset | 20 (57) | 14 (88) | 6 (32) | 0.002 |
| Slurred speech | 9 (26) | 7 (44) | 2 (11) | 0.050 |
| Decreased level of consciousness | 26 (74) | 15 (94) | 11 (58) | 0.022 |
| Convulsions |
8 (23) |
6 (38) |
2 (11) |
0.105 |
| Hemorrhagic manifestations | ||||
| Overall | 12 (34) | 8 (50) | 4 (21) | 0.090 |
| Gross hematuria | 2 (6) | 1 (6) | 1 (5) | 1.000 |
| Petechiae | 3 (9) | 1 (6) | 2 (11) | 1.000 |
| Gingival bleeding | 5 (14) | 3 (19) | 2 (11) | 0.642 |
| Hematemesis | 2 (6) | 1 (6) | 1 (5) | 1.000 |
| Hematochezia | 1 (3) | 1 (6) | 0 (0) | 0.457 |
| Melena |
4 (11) |
4 (25) |
0 (0) |
0.035 |
| Treatment | ||||
| Ribavirin | 9 (26) | 6 (38) | 3 (16) | 0.245 |
| IVIG | 7 (20) | 5 (31) | 2 (11) | 0.208 |
| Plasmapheresis | 7 (20) | 4 (25) | 3 (16) | 0.677 |
| CRRT | 10 (29) | 9 (56) | 1 (5) | 0.002 |
*NA, not applicable; CT, computed tomography; IVIG, intravenous immunoglobulin; CRRT, continuous renal replacement therapy. †Fisher exact test was used to compare groups.