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. Author manuscript; available in PMC: 2015 Oct 5.
Published in final edited form as: Chem Rev. 2006 Feb;106(2):700–719. doi: 10.1021/cr040496t

Figure 7. Principal Steps during Mismatch Repair.

Figure 7

The repair of a T•G mispair generated as a result of replication error is shown. The proteins involved in this repair are shown in a cartoon fashion and identified in the figure. The DNA substrate contains a strand discontinuity (bottom strand) presumably due to a gap between two Okazaki fragments. For details see the text. Adapted from a figure in Ref. 102.