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. 2015 Oct 5;10(10):e0139456. doi: 10.1371/journal.pone.0139456

Fig 4. Determination of the effect of miR–25 on the regulation of SOCS4-suppressed thyroid cancer cell migration and invasion.

Fig 4

(A, B) K1 cells were co-transfected with indicated miR-RNA mimic and plasmid (A) or shRNA (B) for 48 h and allowed to migrate towards serum for 24 h. (C, D) Cell invasion assay experiments were performed with the same conditions as in A and B. (E, F) Wound healing assay experiments were performed with the same conditions as in A and B. (G, H) Cells were transfected with miR–25 inhibitor or control and the experiments were performed as in A and B. (I, J) Cell invasion assay experiments were performed with the same conditions as in G and H. (K, L) Wound healing assay experiments were performed with the same conditions as in G and H. Bar graphs represent mean ± SD, n = 3 (**P < 0.01; *P < 0.05).