Table 4. (α = 0.05) Analysis with a combination of RVs and CVs.

Power in table based on 10000 replicates for each situation with a mix of common and rare variants. The CVs and RVs are all independent of each other.

RVs	OR = (2,2,2,2)				OR = (2, 2, 1/2, 1/2)				OR = (1, 1, 1, 1)
Associated CVs	OR = (1.2,1.2,1.2)				OR = (1.2, 1.2, 0.8)				OR = (1.2,1.2,1.2)
Null CVs	1	5	9	13	1	5	9	13	1	5	9	13
Sum	0.845	0.576	0.428	0.327	0.141	0.098	0.082	0.072	0.430	0.321	0.255	0.207
SKAT	0.496	0.501	0.488	0.490	0.404	0.391	0.390	0.387	0.227	0.169	0.145	0.119
SKAT-C	0.791	0.717	0.674	0.631	0.778	0.684	0.633	0.590	0.494	0.422	0.378	0.327
Seq-aSum	0.729	0.463	0.357	0.292	0.669	0.436	0.341	0.292	0.651	0.446	0.368	0.311
Seq-aSum-VS	0.760	0.523	0.432	0.333	0.672	0.449	0.379	0.304	0.681	0.465	0.412	0.329
LiMB (κ = 0.90)
Average no. branches	1.5	2.3	3.9	8.3	1.7	3.2	6.4	12.6	1.4	1.8	2.7	4.7
Average no. pared branches	1.0	1.1	1.1	1.2	1.1	1.2	1.2	1.2	1.0	1.0	1.0	1.0
wscore	0.233	0.174	0.069	0.049	0.531	0.300	0.167	0.127	0.144	0.129	0.110	0.061
pared wscore	0.230	0.171	0.073	0.053	0.526	0.297	0.174	0.133	0.147	0.130	0.112	0.063
BUR (κ = 0.95)
Average no. branches	8.0	27.8	161	1245	7.2	25.7	137	965	3.6	13.8	78.2	577
Average no. pared branches	2.0	2.5	3.2	4.3	1.9	2.6	3.5	4.9	1.1	1.3	1.7	2.4
wscore	0.766	0.515	0.412	0.316	0.677	0.451	0.371	0.304	0.692	0.466	0.398	0.324
pared wscore	0.761	0.527	0.429	0.329	0.668	0.451	0.374	0.304	0.690	0.481	0.415	0.332
BUR (κ = 0.99)
Average no. branches	1.7	2.3	3.5	5.8	1.8	2.5	3.7	6.0	1.3	1.8	2.7	4.4
Average no. pared branches	1.4	1.6	1.9	2.3	1.6	1.9	2.2	2.7	1.1	1.1	1.3	1.5
wscore	0.761	0.524	0.431	0.333	0.672	0.449	0.377	0.304	0.683	0.466	0.412	0.329
pared wscore	0.760	0.525	0.431	0.334	0.670	0.447	0.376	0.305	0.682	0.469	0.412	0.331