Table 1. Clinical and virological data from 6 vaccinated subjects demonstrated to be HBV DNA positive by both the nested PCR protocol and VERSANT HBV DNA 3.0 assay.
Samples | Sex | Age (years) | ALT (IU/L) a | HBsAg | Anti-HBs b | HBeAg | Anti-HBe c | HBV bDNA (copies/ml) d |
---|---|---|---|---|---|---|---|---|
SS-3-22 | M | 41 | 3 | negative | reactive | negative | reactive | 141465 |
SS-4-7 | F | 36 | 7 | negative | reactive | positive | non-reactive | 5606 |
SS-4-15 | M | 35 | 5 | negative | reactive | positive | non-reactive | 4342 |
SS-4-19 | F | 25 | 9 | negative | reactive | positive | non-reactive | 40152 |
SS-7-5 | F | 38 | 23 | negative | non-reactive | positive | non-reactive | 9374 |
SS-9-43 | M | 63 | 7 | negative | reactive | positive | non-reactive | 27338 |
aThe normal range of ALT (IU/L) is less than or equal to 41.
bAnti-HBs antibody (IU/L): non-reactive < 10 and reactive ≥ 10.
cAnti-HBe antibody (COI): non-reactive > 1.0 and reactive ≤ 1.0.
dThe detection limit of HBV bDNA probe (copies/ml) is greater than or equal to 2000.