Table 7. A MANOVA model of the VMR.

	Pillai*	Pr(>F)
Location	0.3316	< 0.0001
Biological Repeat	0.0150	< 0.0001
Strain	0.0219	< 0.0001
Stage	0.4234	< 0.0001
Technical Repeat	0.0173	< 0.0001
Light Stimulus	0.3772	< 0.0001
Strain:Stage	0.1195	< 0.0001
Strain:Technical_Repeat	0.0171	< 0.0001
Strain:Light_stimulus	0.0506	< 0.0001
Stage:Technical_Repeat	0.0460	< 0.0001
Stage:Light_stimulus	0.2452	< 0.0001
Technical_Repeat: Light_stimulus	0.0236	< 0.0001

*Pillai is the Pillai-Bartlett Trace is the sum of the variance that can be explained by the factors (see Section 2.2.2.3). The sample size in this model is 23268.