Table 2.
Changes in Body Composition and Metabolic Parameters 6 Months After Roux-en-Y Gastric Bypass
| Parameter | Preoperation | 6-month postoperation | % Change | p |
|---|---|---|---|---|
| Body composition | ||||
| Weight (kg) | 125.3 ± 17.8 | 92.8 ± 13.9 | −25.8% ± 5.2% | <0.0001 |
| BMI (kg/m2) | 44.7 ± 7.4 | 33.4 ± 5.8 | −25.4% ± 5.0% | <0.0001 |
| Total body fat (kg) | 56.7 ± 11.4 | 34.0 ± 9.3 | −40.3% ± 9.0% | <0.0001 |
| Total body lean (kg) | 61.8 ± 11.0 | 54.7 ± 9.7 | −11.3% ± 5.2% | <0.0001 |
| Percentage body fat (%) | 46.7 ± 6.3 | 37.0 ± 7.4 | −21.3% ± 7.8% | <0.0001 |
| Visceral fat (cm2) | 199.7 ± 93.5 | 107.2 ± 59.4 | −45.2% ± 17.9% | <0.0001 |
| Waist circumference (cm) | 122.3 ± 13.3 | 98.4 ± 10.5 | −19.1% ± 8.5% | <0.0001 |
| Hip circumference (cm) | 137.3 ± 14.5 | 113.9 ± 12.7 | −17.0% ± 4.1% | 0.0001 |
| Laboratory parameters | ||||
| HbA1c (%) | 5.6 (5.3–6.6) | 5.2 (4.9–5.5) | −10.6% (−17.9% to −6.0%) | <0.0001 |
| Adiponectin (ng/mL) | 4905 (2574–6903) | 8208 (5293–10,100) | +66.0% (+36.2% to +102.9%) | <0.0001 |
| Leptin (ng/mL) | 49.7 (34.5–63.7) | 11.4 (7.0–23.1) | −71.9% (−86.2% to −62.2%) | <0.0001 |
| Estradiol (pg/mL) | 59.4 (44.2–72.9) | 64.7 (42.7–90.0) | +13.7% (−21.5% to +80.0%) | 0.27 |
| IGF-1 (ng/mL) | 108.7 (73.4–138.3) | 128.5 (92.4–153.2) | +8.2% (−3.1% to +48.4%) | 0.03 |
| IGFBP-3 (ng/mL) | 4155 (3227–4907) | 3601 (3262–4158) | −9.6% (−16.4% to −1.7%) | <0.001 |
Values are mean ± SD or median (IQR). Bold p values are significant.
HbA1c = glycated hemoglobin; IGFBP-3 = IGF-binding protein 3; IQR = interquartile range.