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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Mol Cell Neurosci. 2015 Jun 16;68:177–185. doi: 10.1016/j.mcn.2015.06.008

Table 2.

Molar Ratios of Catecholamines Released by Secretagogue Stimulation

Secretagogue Dopamine Norepinephrine Epinephrine Molar Ratio
. pmol/well DA/NE/Epi



KCl 216.8 ± 25.5 4736.0 ± 424.7 8 753.5 ± 846.4 1/22/40
Nicotine 314.2 ± 21.1 6026.6 ± 338.4 12373.5 ± 666.5 1/19/40
Carbachol 404.5 ± 13.6 7092.2 ± 141.4 15294.6 ± 696.5 1/17/38
PACAP 113.5 ± 11.9 2373.9 ± 207.7 5324.6 ± 311.1 1/20/50
Bradykinin 48.1 ± 10.8 1497.0 ± 185.9 4074.3 ± 295.1 1/31/84
Histamine 117.4 ± 11.9 1592.5 ± 159.3 6039.9 ± 252.3 1/14/51

Secretagogue stimulation of catecholamine secretion from chromaffin cells was measured for dopamine (DA), norepinephrine (NE), and epinephrine (Epi) (stimulated amounts of neuropeptides released into the culture media minus basal secretion of each of these catecholamines). Results are shown as mean ± s.e.m. (n = 3). Molar ratios of secreted catecholamines are illustrated for DA/NE/Epi. The average molar ratio for all secretagogues tested was 1.0/20.5/50.5.