Fig. 2.

Effects of wild ginseng CMCs on serum ALT, AST levels (A) and histological changes (B) in the rat liver after GalN (700 mg/kg) injection (original magnification ×400). All values are means ± SD of 10 rats per group. Rats received oral injection of vehicle or wild ginseng CMCs (75, 150, and 300 mg/kg) once daily for 2 wks and 2 h prior to and 6 h after GalN (700 mg/kg) treatment. **p < 0.05, significantly different from control group. ^†p < 0.05, ^††p < 0.01, significantly different from GalN group. Histological features of liver sections stained with H&E at 24 h after GalN injection. Typical images were chosen from each experimental group (original magnification, ×400). Arrow and arrowhead indicate hemorrhagic necrosis and inflammatory cell infiltration, respectively. ALT, alanine aminotransferase; AST, aspartate aminotransferase; CMCs, cambial meristematic cells; H&E, hematoxylin and eosin; GalN, d-galactosamine; SD, standard deviation.