Fig. 3.
Effects of total saponin from Korean Red Ginseng (KRG-TS) on thrombin-induced [Ca2+]i mobilization. (A) Inhibitory effects of KRG-TS on thrombin-induced [Ca2+]i mobilization. (B) Effects of KRG-TS on [Ca2+]i mobilization in the presence of cyclic adenosine monophosphate-dependent protein kinase inhibitor (Rp-8-Br-cAMPS). (C) Effects of KRG-TS on [Ca2+]i mobilization in the presence of cyclic guanosine monophosphate-dependent protein kinase inhibitor (Rp-8-Br-cGMPS). [Ca2+]i was determined as described in the “Materials and methods” section. Data are expressed as the mean ± standard deviation (n = 4). *p < 0.05 versus the thrombin-stimulated human platelets. **p < 0.05 versus the thrombin-stimulated human platelets in the presence of KRG-TS (150 μg/mL). ***p < 0.05 versus the thrombin-stimulated human platelets in the presence of KRG-TS (150 μg/mL).