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. 2015 Mar 28;39(4):354–364. doi: 10.1016/j.jgr.2015.03.006

Table 3.

Effects of protopanaxadiol on thrombin-induced human platelet aggregation

Treatment (μM) Aggregation (%) Treatment (μM) Aggregation (%)
Thrombin (0.05 U/mL) 86.7 ± 1.5
Ginsenoside Ra1 Ginsenoside Rd
 50 83.3 ± 1.2  50 85.0 ± 3.0
 10 83.0 ± 1.7  100 84.0 ± 1.7
 200 83.0 ± 1.0  200 86.3 ± 1.5
 300 86.7 ± 1.5  300 84.3 ± 4.0
Ginsenoside Rb1 Ginsenoside Rg3 (20R)
 50 83.0 ± 1.7  50 86.7 ± 1.5
 100 84.3 ± 0.6  100 86.0 ± 2.0
 200 85.3 ± 3.1  200 75.7 ± 3.2
 300 83.0 ± 3.5  300 62.0 ± 2.0
Ginsenoside Rb2 Ginsenoside Rg3 (20S)
 50 86.7 ± 1.5  50 79.7 ± 2.1 *
 100 84.7 ± 0.6  100 39.7 ± 2.1 **
 200 86.3 ± 2.1  200 9.7 ± 2.1 **
 300 84.7 ± 0.6  300 3.7 ± 1.5 **
Ginsenoside Rb3 Ginsenoside Rh2 (20R)
 50 82.3 ± 3.5  50 83.3 ± 1.2
 100 85.7 ± 1.2  100 84.7 ± 0.6
 200 83.7 ± 1.5  200 85.3 ± 3.1
 300 84.0 ± 3.6  300 81.0 ± 1.7
Ginsenoside Rc
 50 84.7 ± 3.2
 100 84.7 ± 0.6
 200 86.3 ± 2.1
 300 84.0 ± 2.6

Results are expressed as percentage of aggregation induced by thrombin. The data are expressed as the mean ± standard deviation (n = 4)

*p < 0.05, **p < 0.01 versus the thrombin-stimulated human platelets