Fig. 4.

WT and PKU mice fed the GMP diet have altered bacterial populations from WT mice fed the casein (Cas) diet and PKU mice fed the AA diet from weaning through 8–9 wk of age. Relative bacterial phyla abundance was calculated compared with total bacteria in both the cecum (A) and feces (B). In cecal contents from both WT and PKU mice fed the GMP diet there was a significant reduction in the Proteobacteria phylum compared with WT mice fed the casein diet and PKU mice fed the AA diet, P = 0.002 and P = 0.001, respectively. In the feces, PKU mice fed the GMP diet had a significant increase in Bacteroidetes relative to PKU mice fed the AA diet, P = 0.047.