Table 3.
Unadjusted and adjusted Cox proportional-hazards analysis for independent predictors of recurrent disease.
| Characteristic | Unadjusted HR (95%CI) | P | Adjusted HR (95%CI) | P |
|---|---|---|---|---|
| Age (years) | 1 (0.98-1.02) | 0.910 | 1 (0.98-1.03) | 0.844 |
| Male gender | 1.18 (0.54-2.58) | 0.686 | 1.15 (0.35-3.76) | 0.819 |
| Serum 25-hydroxyvitamin D (ng/mL) | 0.99 (0.96-1.02) | 0.349 | 0.99 (0.96-1.02) | 0.608 |
| Vitamin D supplementation | 1.44 (0.64-3.2) | 0.377 | 1.25 (0.33-4.73) | 0.744 |
| Charlson-Deyo score1 | 1.04 (0.9-1.2) | 0.617 | 0.94 (0.72-1.24) | 0.680 |
| ECF resident | 2.04 (0.85-4.9) | 0.111 | 1.93 (0.48-7.73) | 0.352 |
| Previous CDI | 1.31 (0.98-1.74) | 0.067 | 1.44 (0.91-2.28) | 0.116 |
| Detection of stool toxin by EIA | 2.05 (0.90-4.66) | 0.088 | 1.12 (0.38-3.34) | 0.835 |
| Infection with ribotype 027 | 2.55 (0.76-8.58) | 0.131 | 6.09 (0.74-50.49) | 0.094 |
| Serum albumin (g/dL) | 0.64 (0.3-1.37) | 0.246 | 1.28 (0.46-3.59) | 0.641 |
| Severe disease | 1.5 (0.68-3.31) | 0.316 | 1.21 (0.37-3.89) | 0.754 |
BMI, body mass index in kg/m2; CDI, Clostridium difficile infection; CI, confidence interval; ECF, extended care facility; EIA, enzyme immunoassay; HO-HA, healthcare facility-onset, healthcare facility-associated; HR, hazard ratio; y, years.
1weighted comorbidity index.