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. 2015 Oct 6;5:14757. doi: 10.1038/srep14757

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Copyright © 2015, Macmillan Publishers Limited

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FOXP3 expression was determined by flow cytometry in CD3⁺CD56⁺ cells from control liver tissues (n = 4), tumorous (n = 41) and non-tumorous (n = 37) tissues of HCC patients. (a) A representative FACS profile is shown on the left and the percentage of FOXP3⁺ cells in CD3⁺CD56⁺ cells from individual patients are summarized in the right. The numbers denote the percentage of the cell population in the left two quadrants. (b) A correlation analysis was performed between the percentage of FOXP3⁺ cells in the CD3⁺CD56⁺ cell population and that in CD3⁺CD56^– conventional T cell population in the TILs from 41 HCC patients. (c) FOXP3 expression in CD3⁺CD56⁺ cells in TILs and NILs were compared between HCC patients with or without a history of HBV/HCV infection.