Table 1.
Characteristics of patients at baseline and controls
| Characteristics | Patients | Controls |
|---|---|---|
| Participants (n) | 27 | 27 |
| Men (%) | 51.9 | 51.9 |
| Age (yr) | 45.7±9.7 a | 57.6±9.6 |
| Weight (kg) | 81.2±18.4 | 79.2±16.1 |
| Height (cm) | 179±12 | 174±9 |
| Body surface area (m2) | 2.0±0.3 | 1.9±0.2 |
| Systolic BP (mmHg) | 130±11 | 126±21 |
| Diastolic BP (mmHg) | 81±8 a | 74±10 |
| AHT (%) | 77.8 a | 11.1 |
| Serum creatinine (mg/dl) | 1.89±1.13 a | 0.92±0.15 |
| eGFR (ml/min per 1.73 m2) | 52±30 a | 76±10 |
| Urine volume (L/24 hr) | 2.58±0.84 a | 1.69±0.64 |
| Urine osmolality (mOsm/kg) | 359 (281–410) a | 503 (361–649) |
| Urinary urea excretion (g/24 hr) | 23.6 (17.6–29.4) | 20.9 (15.3–25.1) |
| Urinary sodium excretion (mmol/24 hr) | 155 (122–192) | 148 (87–198) |
| mGFR (ml/min) | 70±39 | |
| ERPF (ml/min) | 222±110 | |
| Total kidney volume (ml) | 2147 (1100–2767) |
Values are percentages, means±SD, or medians with interquartile range. AHT, antihypertensives; mGFR, measured GFR; ERPF, effective renal plasma flow.
a
P<0.05 versus controls.