Table 1.

Questions to assist in identifying individuals who may benefit from over-the-counter proton-pump inhibitors versus those who should be referred [9, 12]

Inclusion questions	Exclusion questions
Goal: Identify patient who may benefit from over-the-counter proton-pump inhibitor	Goal: Identify alarm symptoms that should prompt immediate referral
What is the nature of the symptoms you are experiencing?  How frequently are the symptoms occurring?  Have you tried any lifestyle changes or medications that have made your symptoms better or worse?	When did the symptoms start?  Have you experienced any unintentional weight loss, difficulties in or painful swallowing, recurrent cough, hoarseness/changes in voice, blood in faeces or vomit?  Do you have a family history of gastric and/or oesophageal cancer?