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. 2015 Oct 6;5:14833. doi: 10.1038/srep14833

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(A) LytM catalytic domain with the phosphinate transition state analogue; (B) full length LytM with active site blocked by peptide from occluding region (PDB 1QWY); (C,D) catalytic domain of LytM with glycine rich loop from neighboring molecule wedged into the active site cleft (P4₁ (2B13) and P3₂21 (2B44) crystal forms). Arrows mark the direction of the main chain in the transition state analogue and protein fragments occupying in the cleft.