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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Alcohol Clin Exp Res. 2015 Oct;39(10):1863–1877. doi: 10.1111/acer.12810

Figure 1.

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Figure 1

Brain regions important for cocaine (a), methamphetamine (b), alcohol (c), heroin (d) and nicotine (e) self-administration behaviors. Black-filled oval= manipulation of this brain region is important for self-administration behaviors; Gray-filled oval= manipulation of this brain region has no known effects on self-administration behaviors; Open oval= manipulation of this region has not been tested in a similar manner; A line from one region to another indicates a specific projection shown to be important for self-administration-related behaviors. Abbreviations: BLa= basolateral amygdala; CeA= central amygdala; EW= Edinger-Westphal nucleus; Hab= habenula; HIP= hippocampus; IL= infralimbic cortex; LA= lateral amygdala; NAc= nucleus accumbens; PrL= prelimbic cortex; OFC= orbital frontal cortex; VP= ventral pallidum; VTA= ventral tegmental area.