Table 1.

Baseline characteristics of monkeys by treatment and timing of treatment initiation

	Early Menopause			Late Menopause
	Control (n=12)	E2 (n=11)	P	Control (n= 18)	E2 (n= 16)	P
Body weight, kg	2.88 (2.59, 3.21)	3.07 (2.68, 3.51)	0.432	3.21 (2.90, 3.55)	3.30 (3.01, 3.62)	0.676
TPC mmol/L	6.59 (5.35, 8.12)	7.23 (5.90, 8.86)	0.492	8.21 (6.72, 10.04)	9.71 (8.49, 11.10)	0.155
HDLc mmol/L	0.94 (0.82, 1.09)	0.98 (0.78, 1.24)	0.722	1.37 (1.12, 1.69)	1.14 (0.87, 1.50)	0.256
Non-HDLc mmol/L	5.54 (4.31, 7.13)	6.00 (4.49, 8.02)	0.649	6.41 (4.83, 8.51)	8.19 (6.65, 10.09)	0.149
TGs mmol/L	0.30 (0.22, 0.42)	0.26 (0.21, 0.32)	0.398	0.47 (0.39, 0.57)	0.57 (0.44, 0.74)	0.192
TPC/HDLc ratio	7.00 (5.19, 9.45)	7.35 (4.88, 11.07)	0.833	5.98 (4.19, 8.54)	8.50 (6.05, 11.95)	0.143

Data are back-transformed means and (95% confidence intervals) in log scale. E2 = estradiol

The differences between the geometric mean of the control and estradiol groups were assessed with Student t-test.