Table 2.
Hazard ratios for AKI stratified by eGFR and albuminuria categories and by diabetes status for general population cohorts.
| eGFR | No diabetes | Diabetes | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| ACR/Dipstick | ACR/Dipstick | |||||||||
| <10/Dip “−” | 10–29/Dip “±” | 30–299/Dip “1+” | 300+/Dip “≥2+” | <10/Dip “−” | 10–29/Dip “±” | 30–299/Dip “1+” | 300+/Dip “≥2+” | |||
| ≥105 | 1.01 (0.59, 1.70) |
1.89 (0.86, 4.16) |
3.05 (1.37, 6.78) |
9.32 (4.20, 20.67) |
0.82 (0.48, 1.41) |
1.14 (0.57, 2.27) |
1.81 (0.96, 3.42) |
3.04 (1.19, 7.78) |
9.39 (4.16, 21.21) |
1.17 (0.66, 2.08) |
| 90–104 | 0.93 (0.73, 1.18) |
1.36 (0.75, 2.47) |
2.83 (2.13, 3.78) |
6.59 (3.31, 13.13) |
0.90 (0.68, 1.20) |
0.82 (0.63, 1.07) |
1.32 (1.00, 1.73) |
2.40 (1.52, 3.79) |
5.50 (4.19, 7.22) |
0.85 (0.61, 1.20) |
| 75–89 | Ref |
1.97 (1.66, 2.34) |
3.51 (2.68, 4.60) |
6.74 (5.30, 8.58) |
Ref | Ref |
1.70 (1.18, 2.44) |
2.49* (2.11, 2.93) |
4.73* (3.14, 7.12) |
Ref |
| 60–74 |
1.66 (1.53, 1.80) |
2.84 (2.04, 3.95) |
4.48 (3.50, 5.73) |
8.56 (6.75, 10.86) |
1.60 (1.47, 1.73) |
1.36* (1.20, 1.53) |
2.12* (1.80, 2.49) |
3.54* (2.72, 4.60) |
6.82* (5.79, 8.05) |
1.41* (1.30, 1.53) |
| 45–59 |
3.06 (2.41, 3.89) |
5.48 (3.82, 7.86) |
7.41 (5.56, 9.87) |
14.08 (11.16, 17.75) |
2.72 (2.22, 3.34) |
2.89* (2.05, 4.09) |
3.24* (2.15, 4.89) |
4.70* (3.05, 7.24) |
8.75* (5.87, 13.05) |
2.10* (1.63, 2.71) |
| 30–44 |
7.87 (6.03, 10.28) |
9.18 (6.05, 13.94) |
14.29 (9.25, 22.10) |
24.91 (15.31, 40.54) |
5.83 (4.63, 7.36) |
5.27* (3.86, 7.20) |
6.30* (4.16, 9.54) |
9.08* (7.83, 10.54) |
15.62* (10.51, 23.23) |
3.96* (3.41, 4.60) |
| 15–29 |
19.36 (16.91, 22.18) |
25.69 (13.20, 49.99) |
28.46 (23.74, 34.10) |
39.18 (29.32, 52.36) |
10.68 (8.05, 14.17) |
9.80* (7.25, 13.23) |
17.27* (8.34, 35.79) |
15.91* (12.30, 20.58) |
23.53* (16.08, 34.44) |
6.68* (5.57, 8.03) |
| Ref |
1.59 (1.32, 1.93) |
2.58 (2.30, 2.90) |
4.00 (3.16, 5.06) |
Ref |
1.46 (1.25, 1.70) |
2.08* (1.95, 2.22) |
3.44 (2.78, 4.24) |
|||
Hazard ratios which, compared to the reference category, are significantly (p<0.05) greater than 1 are in bold, and significant (p<0.05) interactions with diabetes are indicated with an asterisk in the diabetes subtable. Color shading indicates the strength of association (approximately one quarter of all cells are shaded in each color; Green: low; yellow: mild; orange: moderate; red: high). Units: eGFR (mL/min/1.73m2), ACR (mg/g). Abbreviations: Ref = reference group