Table 3.
Hazard ratios for AKI stratified by eGFR and albuminuria categories and by diabetes status for CKD cohorts.
| eGFR | No diabetes | Diabetes | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| ACR/Dipstick | ACR/Dipstick | |||||||||
| <30/Dip “−/±” | 30–299/Dip “1+” | 300–999/Dip “2+” | 1000+/Dip “≥3+” | <30/Dip “−/±” | 30–299/Dip “1+” | 300–999/Dip “2+” | 1000+/Dip “≥3+” | |||
| ≥75 | 0.85 (0.26, 2.78) |
0.42 (0.21, 0.84) |
1.04 (0.25, 4.37) |
6.16 (0.35, 108.57) |
0.27 (0.08, 0.84) |
0.76 (0.54, 1.07) |
0.42 (0.33, 0.54) |
0.62 (0.37, 1.04) |
2.69 (0.99, 7.27) |
0.34 (0.28, 0.42) |
| 60–74 | 0.71 (0.15, 3.35) |
0.62 (0.26, 1.51) |
1.47 (0.20, 10.83) |
0.48 (0.20, 1.14) |
0.89* (0.69, 1.15) |
2.02 (0.27, 15.10) |
1.22 (0.50, 2.95) |
0.73 (0.10, 5.24) |
0.70 (0.53, 0.92) |
|
| 45–59 | Ref |
1.71 (1.19, 2.45) |
2.49 (1.44, 4.32) |
7.82 (2.63, 23.27) |
Ref | Ref |
1.60 (1.38, 1.86) |
2.26 (1.80, 2.84) |
5.34 (3.77, 7.57) |
Ref |
| 30–44 |
1.74 (1.19, 2.55) |
2.06 (1.28, 3.31) |
2.69 (1.28, 5.66) |
25.29 (6.37, 100.43) |
1.46 (1.10, 1.94) |
1.48 (0.98, 2.25) |
2.27 (1.86, 2.77) |
2.93 (1.59, 5.39) |
2.68* (0.77, 9.38) |
1.34 (1.03, 1.73) |
| 15–29 |
4.90 (2.91, 8.25) |
6.30 (3.72, 10.69) |
7.70 (3.68, 16.11) |
40.72 (14.03, 118.14) |
4.03 (2.90, 5.62) |
3.24 (2.37, 4.44) |
3.89 (2.19, 6.91) |
5.87 (1.25, 27.43) |
13.70 (2.73, 68.89) |
2.46 (1.83, 3.31) |
| Ref |
1.51 (1.17, 1.93) |
2.11 (1.48, 3.01) |
8.04 (4.46, 14.52) |
Ref |
1.38 (1.24, 1.54) |
1.84 (1.47, 2.31) |
3.23* (1.55, 6.71) |
|||
Hazard ratios which, compared to the reference category, are significantly (p<0.05) greater than 1 are in bold, and significant (p<0.05) interactions with diabetes are indicated with an asterisk in the diabetes subtable. Color shading indicates the strength of association (approximately one quarter of all cells are shaded in each color; Green: low; yellow: mild; orange: moderate; red: high). Units: eGFR (mL/min/1.73m2), ACR (mg/g). Abbreviations: Ref = reference group