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. 2015 Aug 18;593(19):4373–4386. doi: 10.1113/JP270701

Figure 5. Acidification does not alter GluA1 expression in pyramidal neurons .

Figure 5

A, Western blot analysis of total and cell surface GluA1 from cultured hippocampal pyramidal neurons (HPNs) 12 h after exposure to either pH 7.4 or pH 6.0. B and C, pooled data from 5 independent cell surface biotinylation experiments demonstrating no change in cell surface expression of GluA1 following acidification (P > 0.05, n = 5). D, Western blot analysis of the ratio of total protein expression level of GluA1 to the total of GluA2 (GluA1/GluA2) following acidification. This ratio increased significantly (0.70 ± 0.12 to 2.0 ± 0.32; P < 0.05, n = 5).