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WTC-01 induced a concentration- and time-dependent G2/M cell arrest in human NPC lines.NPC-TW01 (A, C) and HONE-1 (B, D) cells were treated with IC50 (0.45 μM) of WTC-01 (A, B) for the indicated times or different concentrations (0.225, 0.45 and 0.9 μM) of WTC-01(C, D) for 24 h. The cell cycle population ratios were determined by flow cytometry.
