Figure 6.

WTC-01 treatment reduces the migratory ability of human NPC cells. Confluent cell cultures of NPC-TW01 (A) and HONE-1 (B) were wounded by scratching with a plastic micropipette tip, suspended cells were then removed by PBS washes and then treated with different concentrations (0.25,0.5 and 1 x IC50) of WTC-01. Cells were photographed at the indicated times after wounding by phase contrast microscopy (×100). The percentage of area wound healing of cells was quantified, and values shown are means ± SD from triplicate experiments. *P < 0.05, **P < 0.01, significantly different as indicated; one-way ANOVA.