Figure 2.

UASp-Cdk1-VFP transgenes expressed in imaginal wing or eye discs with sd-Gal4 or ey-Gal4, respectively, cause distinct phenotypic effects. Panels A to D show adult wings of progeny expressing the indicated transgenes in an otherwise wild-type background. Expression of Cdk1(WT), Cdk1(T14A) or Cdk1(Y15F) caused no detectable defects in adult wing morphology (A–C), whereas expression of Cdk1(T14A,Y15F) resulted in wing margin defects (D). (E–H) Scanning electron micrographs of adult eyes. Expression of Cdk1(WT), Cdk1(T14A) or Cdk1(Y15F) did not affect adult eye development (E–G), however Cdk1(T14A,Y15F) produced severe defects in adult eye and head structures resulting in pharate adult lethality. © Genetics Society of America. Reproduced with permission from Genetics Society of America. Permission to reuse must be obtained by the copyright holder.³⁹