Figure 2.

Elevated cell density in the molecular layer of P12 Pfn1^{flx/flx,Math1-Cre} mice. (A and B) Propidium iodide-stained cerebellar sections of a Pfn1^flx/flx control and a Pfn1^{flx/flx,Math1-Cre} mouse at P12. Scale bar in A corresponds to 750 μm. (C) Layer thickness of the cerebellar cortex in tamoxifen- and corn oil-treated mice. IGL width, but not ML or EGL width, was reduced in tamoxifen-treated Pfn1^{flx/flx,Math1-Cre} mice. No changes were observed in corn oil-treated Pfn1^{flx/flx,Math1-Cre} controls. (D and E) Propidium iodide-stained folia 4 at high magnification. Scale bar in D corresponds to 40 μm. (F) ML cell density was increased in tamoxifen-injected Pfn1^flx/flx mice at P12, but not in corn oil-treated Pfn1^{flx/flx,Math1-Cre} controls. ns: not significant, ***: P < 0.001.