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. 2015 Oct 6;9:388. doi: 10.3389/fncel.2015.00388

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Copyright © 2015 Zhang, Song, Gu, Ren, Verkhratsky and Peng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of MPTP on motor activity. C57BL/6 mice were treated with MPTP (25 mg/kg/d, 7 days, i.p.). Test was done on the 3rd day, 7th day (1 day after the cease of MPTP treatment), 14th day (7 days after the cease of MPTP treatment) and 21th day (14 days after the cease of MPTP treatment). (A) The rotarod test. The latency to fall off the rotarod was recorded. The values are expressed as the mean ± SEM, n = 6, *Indicates statistically significant (p < 0.05) difference from other groups at the same treatment period. (B) T-turn time. The time taken for the mice to turn completely downward in the pole test. The values are expressed as the mean ± SEM, n = 6, *Indicates statistically significant (p < 0.05) difference from other groups at the same treatment period. (C) T-LA time. The time taken for the mice to reach the floor in the pole test. The values are expressed as the mean ± SEM, n = 6, *Indicates statistically significant (p < 0.05) difference from other groups at the same treatment period.