Skip to main content
. 2015 Oct 6;9:388. doi: 10.3389/fncel.2015.00388

Table 1.

Effect of MPTP on sickness behaviors (body weight changes, locomotor activity and social exploratory behavior).

0 Day 3 Days 7 Days 14 Days 21 Days
Body weight changes (%) Saline −1.11 ± 1.38 −0.75 ± 0.62 −0.64 ± 1.39 −0.67 ± 1.28
(n = 15) (n = 15) (n = 15) (n = 18)
MPTP −4.30 ± 1.02 −5.95 ± 1.07* −5.25 ± 0.99* −0.05 ± 1.18
(n = 13) (n = 25) (n = 22) (n = 14)
Lines crossed Saline 57.17 ± 5.18 51.50 ± 8.84 54.33 ± 7.80 57.50 ± 6.30 50.00 ± 6.13
(n = 6) (n = 6) (n = 6) (n = 6) (n = 6)
MPTP 47.00 ± 7.00 49.12 ± 5.98 52.71 ± 5.44 55.86 ± 4.91 50.86 ± 4.80
(n = 7) (n = 7) (n = 7) (n = 7) (n = 7)
Social exploration (s) Saline 147.00 ± 18.15 146.60 ± 11.27 150.00 ± 23.00 152.20 ± 8.29 171.60 ± 13.19
(n = 5) (n = 5) (n = 5) (n = 5) (n = 5)
MPTP 151.20 ± 13.38 150.67 ± 14.95 161.83 ± 18.16 139.67 ± 12.83 152.33 ± 6.56
(n = 5) (n = 6) (n = 6) (n = 6) (n = 6)

*Significantly different from the corresponding saline group (p < 0.05).