Table 1.
0 Day | 3 Days | 7 Days | 14 Days | 21 Days | ||
---|---|---|---|---|---|---|
Body weight changes (%) | Saline | – | −1.11 ± 1.38 | −0.75 ± 0.62 | −0.64 ± 1.39 | −0.67 ± 1.28 |
(n = 15) | (n = 15) | (n = 15) | (n = 18) | |||
MPTP | – | −4.30 ± 1.02 | −5.95 ± 1.07* | −5.25 ± 0.99* | −0.05 ± 1.18 | |
(n = 13) | (n = 25) | (n = 22) | (n = 14) | |||
Lines crossed | Saline | 57.17 ± 5.18 | 51.50 ± 8.84 | 54.33 ± 7.80 | 57.50 ± 6.30 | 50.00 ± 6.13 |
(n = 6) | (n = 6) | (n = 6) | (n = 6) | (n = 6) | ||
MPTP | 47.00 ± 7.00 | 49.12 ± 5.98 | 52.71 ± 5.44 | 55.86 ± 4.91 | 50.86 ± 4.80 | |
(n = 7) | (n = 7) | (n = 7) | (n = 7) | (n = 7) | ||
Social exploration (s) | Saline | 147.00 ± 18.15 | 146.60 ± 11.27 | 150.00 ± 23.00 | 152.20 ± 8.29 | 171.60 ± 13.19 |
(n = 5) | (n = 5) | (n = 5) | (n = 5) | (n = 5) | ||
MPTP | 151.20 ± 13.38 | 150.67 ± 14.95 | 161.83 ± 18.16 | 139.67 ± 12.83 | 152.33 ± 6.56 | |
(n = 5) | (n = 6) | (n = 6) | (n = 6) | (n = 6) |
*Significantly different from the corresponding saline group (p < 0.05).