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. 2014 Dec 13;8(3):176–187. doi: 10.4161/19336934.2014.983389

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© 2014 The Author(s). Published with license by Taylor & Francis Group, LLC

© Sergey A Fedotov, Julia V Bragina, Natalia G Besedina, Larisa V Danilenkova, Elena A Kamysheva, Anna A Panova, and Nikolai G Kamyshev

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 1. — Locomotion parameters in flies with tissue-specific knockdown of the candidate genes (VDRC RNAi lines). GAL4/UAS-RNAi flies with spatially restricted knockdown (second column for each driver) derived by crossing elav/nrv2/appl/tsh-GAL4 drivers with VDRC RNAi lines. GAL4 controls without UAS-RNAi transgene (first, hatched columns) originate from cross of the same GAL4 drivers with host strain #60100 and are specific for each GAL4 driver. Also presented are locomotion parameters in UAS-RNAi controls descended from cross of CS_BDSC with VDRC RNAi line for a gene indicated (CS, second columns) and in flies derived by crossing CS_BDSC with host strain #60100 (CS, first, hatched column). Mean values with standard errors are shown. N = 40 for each data point. Significant difference from a corresponding control is indicated by filling (2-sided randomization test, 10,000 iterations, P < 0.05). Comparisons excluded from consideration (see text) are marked with asterisk. For details of genotypes see Methods and Table 2.