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. 2014 Oct 30;8(6):519–527. doi: 10.4161/19336950.2014.967623

Figure 5.

Figure 5.

Pre-treatment of RGCs with PKC antagonist GF109203X reduced the actions of L-803, 087. (A) Calcium channel currents in isolated RGCs pretreated (p/t) with GFX (left: 1 μM, right: 5 μM). Administration of L-803,087 (left: gray; right: bold) reduced calcium channel currents compared to pre-treatment conditions (regular trace). (B) The mean data show that after cells were pre-treated with 1 μM GFX, L-803,087 reduced calcium channel current (n = 11; *P < 0.05, 2-way RM ANOVA vs. 1 μM GFX p/t). C. Pre-treatment of cells with 5 μM GFX reduced the effect of L-803,087 on calcium channel current (n = 8; *P < 0.05, 2-way RM ANOVA vs. 5 μM GFX p.t).