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Effect of periostin on proliferation and the cell cycle in activated HSC. (A) siRNA-periostin reversed TGF-β1-increased BrdU incorporation; (B) cell cycle progression was evaluated by flow cytometry; (C) percentages of cell cycle distribution among different groups are presented as a histogram graph. The experiments were repeated three times and the data are shown as means ± SD. *P < 0.05 versus control; #P < 0.05 versus TGF-β1.
