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. 2015 Jul 14;80(4):706–715. doi: 10.1111/bcp.12680

Table 2.

Exposure–response analysis: Key parameters for the primary model

Contrast Estimate 90% CI
Lower Upper
Slope OZ439 (ms per ng ml−1) 0.00216 −0.00021 0.00453
Slope piperaquine (ms per ng ml−1) 0.04747 0.03839 0.05654
Offset combination therapy vs. placebo (ms) 1.9 −1.0 4.8

Estimates are based on a model without interaction between the drugs.