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. Author manuscript; available in PMC: 2016 Apr 15.
Published in final edited form as: J Immunol. 2015 Sep 9;195(8):3716–3724. doi: 10.4049/jimmunol.1500753

Figure 6. Repertoire profile of clones shared between blood and spleen.

Figure 6

Analysis of clones shared between blood and spleen for IgG and IgA (A), and IgM subsets (B). Abbreviations and criteria of repertoire analysis are depicted in legend to Figure 5 with the addition of tissue: blood (bl) and spleen (sp). (C) 2D plot representation according to mutation frequency and Vh4 usage of the clones shared between blood and spleen for Mem_G (blue), Mem_A (green) and MZ (red) B cells, together with the profile of the parental blood and spleen subsets. Spleen sequences are represented by squares, blood sequences by dots, and sequences shared between blood and spleen by a hexagon framed in black. Circles mark the closest parental subset of the clones shared between both tissues.