Table 1. General concepts for improvement of safety of immunotherapy vaccines.
Strategies | IgE reactivity |
T-cell reactivity |
---|---|---|
T-cell peptides | − | + |
Recombinant technology (mutants, fragments, oligomers and hybrids) |
reduced | + |
Peptide-carrier fusion proteins |
− | − |
IgE, immunoglobulin E.