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. Author manuscript; available in PMC: 2015 Oct 6.
Published in final edited form as: Curr Opin Allergy Clin Immunol. 2012 Oct;12(5):555–563. doi: 10.1097/ACI.0b013e328357ca53

Table 1. General concepts for improvement of safety of immunotherapy vaccines.

Strategies IgE
reactivity
T-cell
reactivity
T-cell peptides +
Recombinant technology
(mutants, fragments,
oligomers and hybrids)
reduced +
Peptide-carrier fusion
proteins

IgE, immunoglobulin E.